Treatment Guide · Evidence-Based Care

Medication-Assisted Treatment (MAT) for Addiction Recovery

Medication-Assisted Treatment combines FDA-approved medications such as buprenorphine (Suboxone), methadone, or naltrexone (Vivitrol) with counseling and behavioral therapies. MAT is clinically proven to reduce opioid us...

Last reviewed Apr 29, 2026 SAMHSA & NIDA sourced Peninsula Editorial Team
Duration
Ongoing (12+ months recommended)
Typical cost
$5,000 - $15,000/year
Insurance
Required to be covered under ACA
Success rate
60-75%
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Overview

Medication-Assisted Treatment combines FDA-approved medications such as buprenorphine (Suboxone), methadone, or naltrexone (Vivitrol) with counseling and behavioral therapies. MAT is clinically proven to reduce opioid use, prevent overdose deaths, decrease criminal activity, and improve treatment retention rates.

What the Research and Authorities Say

Medication-Assisted Treatment is endorsed by SAMHSA as the gold standard for opioid and alcohol use disorder. NIDA research shows MAT reduces opioid overdose deaths by more than 50%, cuts illicit opioid use by 40-60%, and increases treatment retention by two to four times compared to counseling alone. The FDA has approved three medications for opioid use disorder — buprenorphine (Suboxone), methadone, and naltrexone (Vivitrol) — and four for alcohol use disorder. The ASAM National Practice Guideline recommends medication as first-line care; withholding it without clinical justification is considered below the standard of care.

Who Is It For?

MAT is most effective for individuals with opioid use disorder (heroin, fentanyl, prescription painkillers) or alcohol use disorder. It stabilizes brain chemistry, blocks euphoric effects, and relieves cravings so the person can focus on recovery.

What Does It Include?

  • Comprehensive medical assessment
  • FDA-approved medications
  • Individual and group counseling
  • Regular drug screening
  • Psychiatric support
  • Care coordination
  • Peer support and recovery coaching
  • Ongoing monitoring and dosage adjustments

Frequently Asked Questions

What is medication-assisted treatment (mat)?

Medication-Assisted Treatment combines FDA-approved medications such as buprenorphine (Suboxone), methadone, or naltrexone (Vivitrol) with counseling and behavioral therapies. MAT is clinically proven to reduce opioid use, prevent overdose deaths, decrease criminal activity, and improve treatment retention rates.

Who should consider medication-assisted treatment (mat)?

MAT is most effective for individuals with opioid use disorder (heroin, fentanyl, prescription painkillers) or alcohol use disorder. It stabilizes brain chemistry, blocks euphoric effects, and relieves cravings so the person can focus on recovery.

How long does medication-assisted treatment (mat) last?

Typical duration is Ongoing (12+ months recommended). Length should be individualized based on clinical assessment and progress.

How much does medication-assisted treatment (mat) cost?

Average cost is $5,000 - $15,000/year. Required to be covered under ACA. Many facilities offer sliding-scale fees. Call (254) 360-8759 to verify coverage.

What is the success rate?

Success rates are approximately 60-75%. Success improves with longer treatment, aftercare, and addressing co-occurring disorders.

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Medical Disclaimer

This guide is for informational purposes only and does not constitute medical advice. Treatment decisions should be made with a qualified healthcare provider. For immediate help, call SAMHSA National Helpline 1-800-662-HELP (4357) or 911 in an emergency. For confidential benefits verification, call (254) 360-8759.

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